The AQP2 mutation V71M causes nephrogenic diabetes insipidus in humans but does not impair the function of a bacterial homolog

Several point mutations have been identified in human aquaporins, but their effects on the function of the respective aquaporins are mostly enigmatic. We analyzed the impact of the aquaporin 2 mutation V71M, which causes nephrogenic diabetes insipidus in humans, on aquaporin structure and activity,...

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Detalles Bibliográficos
Autores principales: Klein, Noreen, Kümmerer, Nadine, Hobernik, Dominika, Schneider, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552806/
https://www.ncbi.nlm.nih.gov/pubmed/26442203
http://dx.doi.org/10.1016/j.fob.2015.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552806/
https://www.ncbi.nlm.nih.gov/pubmed/26442203
http://dx.doi.org/10.1016/j.fob.2015.07.003

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