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The AQP2 mutation V71M causes nephrogenic diabetes insipidus in humans but does not impair the function of a bacterial homolog
Several point mutations have been identified in human aquaporins, but their effects on the function of the respective aquaporins are mostly enigmatic. We analyzed the impact of the aquaporin 2 mutation V71M, which causes nephrogenic diabetes insipidus in humans, on aquaporin structure and activity,...
Autores principales: | Klein, Noreen, Kümmerer, Nadine, Hobernik, Dominika, Schneider, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552806/ https://www.ncbi.nlm.nih.gov/pubmed/26442203 http://dx.doi.org/10.1016/j.fob.2015.07.003 |
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