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Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in Obesity

Obesity-induced inflammation in visceral adipose tissue (VAT) is a major contributor to insulin resistance and type 2 diabetes. Whereas innate immune cells, notably macrophages, contribute to visceral adipose tissue (VAT) inflammation and insulin resistance, the role of adaptive immunity is less wel...

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Detalles Bibliográficos
Autores principales: Subramanian, Manikandan, Ozcan, Lale, Ghorpade, Devram Sampat, Ferrante, Anthony W., Tabas, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552860/
https://www.ncbi.nlm.nih.gov/pubmed/26317499
http://dx.doi.org/10.1371/journal.pone.0135842