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Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in Obesity
Obesity-induced inflammation in visceral adipose tissue (VAT) is a major contributor to insulin resistance and type 2 diabetes. Whereas innate immune cells, notably macrophages, contribute to visceral adipose tissue (VAT) inflammation and insulin resistance, the role of adaptive immunity is less wel...
Autores principales: | Subramanian, Manikandan, Ozcan, Lale, Ghorpade, Devram Sampat, Ferrante, Anthony W., Tabas, Ira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552860/ https://www.ncbi.nlm.nih.gov/pubmed/26317499 http://dx.doi.org/10.1371/journal.pone.0135842 |
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