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Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes

Direct exposure of cardiomyocytes to ethanol causes cardiac damage such as cardiac arrythmias and apoptotic cell death. Cardiomyocytes are connected to each other through intercalated disks (ID), which are composed of a gap junction (GJ), adherens junction, and desmosome. Changes in the content as w...

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Detalles Bibliográficos
Autores principales: Noritake, Kanako, Aki, Toshihiko, Funakoshi, Takeshi, Unuma, Kana, Uemura, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552866/
https://www.ncbi.nlm.nih.gov/pubmed/26317911
http://dx.doi.org/10.1371/journal.pone.0136952