Cargando…

Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis

IL-17 is a pro-inflammatory cytokine implicated in the pathogenesis of glomerulonephritis and IL-17 deficient mice are protected from nephrotoxic nephritis. However, a regulatory role for IL-17 has recently emerged. We describe a novel protective function for IL-17 in the kidney. Bone marrow chimera...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamour, Sally, Gan, Poh-Yi, Pepper, Ruth, Florez Barros, Fernanda, Wang, Hsu-Han, O’Sullivan, Kim, Iwakura, Yoichiro, Cook, Terence, Pusey, Charles, Holdsworth, Stephen, Salama, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552867/
https://www.ncbi.nlm.nih.gov/pubmed/26317864
http://dx.doi.org/10.1371/journal.pone.0136238