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Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer

BACKGROUND: The phosphoinositide 3-kinase (PI3K)/protein kinase B (PKB, AKT)/mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in angiogenesis and cell growth, proliferation, metabolism, migration, differentiation, and apoptosis. Genetic diversity in key factors of this pa...

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Detalles Bibliográficos
Autores principales: Piao, Ying, Li, Ying, Xu, Qian, Liu, Jing-wei, Xing, Cheng-zhong, Xie, Xiao-dong, Yuan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552869/
https://www.ncbi.nlm.nih.gov/pubmed/26317520
http://dx.doi.org/10.1371/journal.pone.0136447