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Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer
BACKGROUND: The phosphoinositide 3-kinase (PI3K)/protein kinase B (PKB, AKT)/mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in angiogenesis and cell growth, proliferation, metabolism, migration, differentiation, and apoptosis. Genetic diversity in key factors of this pa...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552869/ https://www.ncbi.nlm.nih.gov/pubmed/26317520 http://dx.doi.org/10.1371/journal.pone.0136447 |