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Comparison of Major and Minor Viral SNPs Identified through Single Template Sequencing and Pyrosequencing in Acute HIV-1 Infection

Massively parallel sequencing (MPS) technologies, such as 454-pyrosequencing, allow for the identification of variants in sequence populations at lower levels than consensus sequencing and most single-template Sanger sequencing experiments. We sought to determine if the greater depth of population s...

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Detalles Bibliográficos
Autores principales: Iyer, Shyamala, Casey, Eleanor, Bouzek, Heather, Kim, Moon, Deng, Wenjie, Larsen, Brendan B., Zhao, Hong, Bumgarner, Roger E., Rolland, Morgane, Mullins, James I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552882/
https://www.ncbi.nlm.nih.gov/pubmed/26317928
http://dx.doi.org/10.1371/journal.pone.0135903