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A Subregion of Reelin Suppresses Lipoprotein-Induced Cholesterol Accumulation in Macrophages
Activation of apolipoprotein E receptor-2 (apoER2) and very low density lipoprotein receptor (VLDLR) inhibits foam cell formation. Reelin is a ligand of these receptors. Here we generated two reelin subregions containing the receptor binding domain with or without its C-terminal region (R5-6C and R5...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552883/ https://www.ncbi.nlm.nih.gov/pubmed/26317415 http://dx.doi.org/10.1371/journal.pone.0136895 |