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C/EBPβ Promotes Immunity to Oral Candidiasis through Regulation of β-Defensins

Humans or mice subjected to immunosuppression, such as corticosteroids or anti-cytokine biologic therapies, are susceptible to mucosal infections by the commensal fungus Candida albicans. Recently it has become evident that the Th17/IL-17 axis is essential for immunity to candidiasis, but the downst...

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Detalles Bibliográficos
Autores principales: Simpson-Abelson, Michelle R., Childs, Erin E., Ferreira, M. Carolina, Bishu, Shrinivas, Conti, Heather R., Gaffen, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552893/
https://www.ncbi.nlm.nih.gov/pubmed/26317211
http://dx.doi.org/10.1371/journal.pone.0136538