Haplotype-based approach to known MS-associated regions increases the amount of explained risk

Genome-wide association studies (GWAS), using single nucleotide polymorphisms (SNPs), have yielded 110 non-human leucocyte antigen genomic regions that are associated with multiple sclerosis (MS). Despite this large number of associations, however, only 28% of MS-heritability can currently be explai...

Descripción completa

Detalles Bibliográficos
Autores principales: Khankhanian, Pouya, Gourraud, Pierre-Antoine, Lizee, Antoine, Goodin, Douglas S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Complex Traits
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552900/
https://www.ncbi.nlm.nih.gov/pubmed/26185143
http://dx.doi.org/10.1136/jmedgenet-2015-103071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552900/
https://www.ncbi.nlm.nih.gov/pubmed/26185143
http://dx.doi.org/10.1136/jmedgenet-2015-103071

Ejemplares similares