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Haplotype-based approach to known MS-associated regions increases the amount of explained risk

Genome-wide association studies (GWAS), using single nucleotide polymorphisms (SNPs), have yielded 110 non-human leucocyte antigen genomic regions that are associated with multiple sclerosis (MS). Despite this large number of associations, however, only 28% of MS-heritability can currently be explai...

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Detalles Bibliográficos
Autores principales:	Khankhanian, Pouya, Gourraud, Pierre-Antoine, Lizee, Antoine, Goodin, Douglas S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2015
Materias:	Complex Traits
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552900/ https://www.ncbi.nlm.nih.gov/pubmed/26185143 http://dx.doi.org/10.1136/jmedgenet-2015-103071

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