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Metformin can block precancerous progression to invasive tumors of bladder through inhibiting STAT3-mediated signaling pathways
BACKGROUND: Metformin is the first line of oral antidiabetic drug in the biguanide class for treatment of type 2 diabetes. Increasing evidence has suggested that it is a potential anti-tumor drug. However, the mechanisms underlying inhibiting tumor development remain elusive, especially in bladder t...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553001/ https://www.ncbi.nlm.nih.gov/pubmed/26245871 http://dx.doi.org/10.1186/s13046-015-0183-0 |