Metformin can block precancerous progression to invasive tumors of bladder through inhibiting STAT3-mediated signaling pathways

BACKGROUND: Metformin is the first line of oral antidiabetic drug in the biguanide class for treatment of type 2 diabetes. Increasing evidence has suggested that it is a potential anti-tumor drug. However, the mechanisms underlying inhibiting tumor development remain elusive, especially in bladder t...

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Detalles Bibliográficos
Autores principales: Pan, Qi, Yang, Guo-Liang, Yang, Jiang-Hua, Lin, Shi-Long, Liu, Ning, Liu, Shan-Shan, Liu, Meng-Yao, Zhang, Lian-Hua, Huang, Yi-Ran, Shen, Ru-long, Liu, Qiang, Gao, Jian-Xin, Bo, Juan-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553001/
https://www.ncbi.nlm.nih.gov/pubmed/26245871
http://dx.doi.org/10.1186/s13046-015-0183-0

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