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Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer
BACKGROUND: The NIMA-related kinase 2 (NEK2) is a serine/threonine kinase that is involved in regulation of centrosome duplication and spindle assembly during mitosis. Dysregulation of these processes causes chromosome instability and aneuploidy, which are hallmark changes of many solid tumors. Howe...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553013/ https://www.ncbi.nlm.nih.gov/pubmed/26320076 http://dx.doi.org/10.1186/s12894-015-0085-7 |