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Adaptive changes in the kinetochore architecture facilitate proper spindle assembly

Mitotic spindle formation relies on the stochastic capture of microtubules at kinetochores. Kinetochore architecture affects the efficiency and fidelity of this process with large kinetochores expected to accelerate assembly at the expense of accuracy, and smaller kinetochores to suppress errors at...

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Detalles Bibliográficos
Autores principales: Magidson, Valentin, Paul, Raja, Yang, Nachen, Ault, Jeffrey G., O’Connell, Christopher B., Tikhonenko, Irina, McEwen, Bruce F., Mogilner, Alex, Khodjakov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553083/
https://www.ncbi.nlm.nih.gov/pubmed/26258631
http://dx.doi.org/10.1038/ncb3223