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Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer

BACKGROUND: Post-transcriptional regulation by heterogeneous ribonucleoproteins (hnRNPs) is an important regulatory paradigm in cancer development. Our proteomic analysis revealed hnRNPD overexpression in oral dysplasia as compared with normal mucosa; its role in oral carcinogenesis remains unknown....

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Detalles Bibliográficos
Autores principales: Kumar, Manish, Matta, Ajay, Masui, Olena, Srivastava, Gunjan, Kaur, Jatinder, Thakar, Alok, Shukla, Nootan Kumar, RoyChoudhury, Ajoy, Sharma, Meherchand, Walfish, Paul G., Michael Siu, K. W., Chauhan, Shyam Singh, Ralhan, Ranju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553214/
https://www.ncbi.nlm.nih.gov/pubmed/26318153
http://dx.doi.org/10.1186/s12967-015-0637-3