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Promyelocytic Leukemia with No Retinoic Acid Receptor Alpha Abnormality but with RUNX1T1 Insertion to Chromosome 7q: A Classification and Management Dilemma

A case of acute promyelocytic leukemia (APL) with RUNX1T1 insertion to 7q is described and compared to reported cases of APL with negative retinoic acid receptor alpha (RARA) abnormality. In this report, we describe the case of a 2-year-old boy who presented with bone pain and was found to have panc...

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Detalles Bibliográficos
Autores principales: Overholt, Kathleen, Guinipero, Terri L., Heerema, Nyla A., Loken, Michael R., Kahwash, Samir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553303/
https://www.ncbi.nlm.nih.gov/pubmed/26351594
http://dx.doi.org/10.1155/2015/412016