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Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes

BACKGROUND: CD300LG rs72836561 (c.313C>T, p.Arg82Cys) has in genetic-epidemiological studies been associated with the lipoprotein abnormalities of the metabolic syndrome. CD300LG belongs to the CD300-family of membrane-bound molecules which have the ability to recognize and interact with extracel...

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Detalles Bibliográficos
Autores principales: Støy, Julie, Kampmann, Ulla, Mengel, Annette, Magnusson, Nils E, Jessen, Niels, Grarup, Niels, Rungby, Jørgen, Stødkilde-Jørgensen, Hans, Brandslund, Ivan, Christensen, Cramer, Hansen, Torben, Pedersen, Oluf, Møller, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553907/
https://www.ncbi.nlm.nih.gov/pubmed/26336608
http://dx.doi.org/10.1136/bmjdrc-2015-000095