Growth Retardation, General Hypotonia, and Loss of Acquired Neuromotor Skills in the Infants of Mothers With Cobalamin Deficiency and the Possible Role of Succinyl-CoA and Glycine in the Pathogenesis

Vitamin B(12) (cobalamin, Cbl) deficiency can cause metabolic, hematological, and neurological abnormalities. Adequate levels of succinyl-coenzyme A (CoA) cannot be synthesized from methylmalonyl-CoA because of the decreased activity of the methylmalonyl-CoA mutase enzyme that uses Cbl as the cofact...

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Detalles Bibliográficos
Autor principal: Bicakci, Zafer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
4800
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553967/
https://www.ncbi.nlm.nih.gov/pubmed/25738478
http://dx.doi.org/10.1097/MD.0000000000000584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553967/
https://www.ncbi.nlm.nih.gov/pubmed/25738478
http://dx.doi.org/10.1097/MD.0000000000000584

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