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Medium-Based Noninvasive Preimplantation Genetic Diagnosis for Human α-Thalassemias(-SEA)

To develop a noninvasive medium-based preimplantation genetic diagnosis (PGD) test for α-thalassemias(-SEA). The embryos of α-thalassemia(-SEA) carriers undergoing in vitro fertilization (IVF) were cultured. Single cells were biopsied from blastomeres and subjected to fluorescent gap polymerase chai...

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Detalles Bibliográficos
Autores principales: Wu, Haitao, Ding, Chenhui, Shen, Xiaoting, Wang, Jing, Li, Rong, Cai, Bing, Xu, Yanwen, Zhong, Yiping, Zhou, Canquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554004/
https://www.ncbi.nlm.nih.gov/pubmed/25816038
http://dx.doi.org/10.1097/MD.0000000000000669