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Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all

The currently available arsenal of anticancer modalities includes many DNA damaging agents that can kill malignant cells. However, efficient DNA repair mechanisms protect both healthy and cancer cells against the effects of treatment and contribute to the development of drug resistance. Therefore, a...

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Detalles Bibliográficos
Autores principales: Oei, Arlene L., Vriend, Lianne E. M., Crezee, Johannes, Franken, Nicolaas A. P., Krawczyk, Przemek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554295/
https://www.ncbi.nlm.nih.gov/pubmed/26245485
http://dx.doi.org/10.1186/s13014-015-0462-0