Cationic PLGA/Eudragit RL nanoparticles for increasing retention time in synovial cavity after intra-articular injection in knee joint

Positively surface-charged poly(lactide-co-glycolide) (PLGA)/Eudragit RL nanoparticles (NPs) were designed to increase retention time and sustain release profile in joints after intra-articular injection, by forming micrometer-sized electrostatic aggregates with hyaluronic acid, an endogenous anioni...

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Detalles Bibliográficos
Autores principales: Kim, Sung Rae, Ho, Myoung Jin, Lee, Eugene, Lee, Joon Woo, Choi, Young Wook, Kang, Myung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554397/
https://www.ncbi.nlm.nih.gov/pubmed/26345227
http://dx.doi.org/10.2147/IJN.S88363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554397/
https://www.ncbi.nlm.nih.gov/pubmed/26345227
http://dx.doi.org/10.2147/IJN.S88363

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