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Cationic PLGA/Eudragit RL nanoparticles for increasing retention time in synovial cavity after intra-articular injection in knee joint

Positively surface-charged poly(lactide-co-glycolide) (PLGA)/Eudragit RL nanoparticles (NPs) were designed to increase retention time and sustain release profile in joints after intra-articular injection, by forming micrometer-sized electrostatic aggregates with hyaluronic acid, an endogenous anioni...

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Detalles Bibliográficos
Autores principales:	Kim, Sung Rae, Ho, Myoung Jin, Lee, Eugene, Lee, Joon Woo, Choi, Young Wook, Kang, Myung Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554397/ https://www.ncbi.nlm.nih.gov/pubmed/26345227 http://dx.doi.org/10.2147/IJN.S88363

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