Dual actions of albumin packaging and tumor targeting enhance the antitumor efficacy and reduce the cardiotoxicity of doxorubicin in vivo

Doxorubicin (DOX) is an effective chemotherapy drug used to treat different types of cancers. However, DOX has severe side effects, especially life-threatening cardiotoxicity. We herein report a new approach to reduce the toxicity of DOX by embedding DOX inside human serum albumin (HSA). HSA is furt...

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Detalles Bibliográficos
Autores principales: Zheng, Ke, Li, Rui, Zhou, Xiaolei, Hu, Ping, Zhang, Yaxin, Huang, Yunmei, Chen, Zhuo, Huang, Mingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554405/
https://www.ncbi.nlm.nih.gov/pubmed/26346331
http://dx.doi.org/10.2147/IJN.S84478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554405/
https://www.ncbi.nlm.nih.gov/pubmed/26346331
http://dx.doi.org/10.2147/IJN.S84478

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