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Gene expression regulation in retinal pigment epithelial cells induced by viral RNA and viral/bacterial DNA

PURPOSE: The pathogenesis of age-related macular degeneration (AMD) is associated with systemic and local inflammation. Various studies suggested that viral or bacterial infection may aggravate retinal inflammation in the aged retina. We compared the effects of synthetic viral RNA (poly(I:C)) and vi...

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Detalles Bibliográficos
Autores principales: Brosig, Anton, Kuhrt, Heidrun, Wiedemann, Peter, Kohen, Leon, Bringmann, Andreas, Hollborn, Margrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554413/
https://www.ncbi.nlm.nih.gov/pubmed/26330750