Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease

OBJECTIVE: Pelizaeus–Merzbacher disease (PMD) is a progressive and lethal leukodystrophy caused by mutations affecting the proteolipid protein (PLP1) gene. The most common cause of PMD is a duplication of PLP1 and at present there is no curative therapy available. METHODS: By using transgenic mice c...

Descripción completa

Detalles Bibliográficos
Autores principales: Epplen, Dirk B, Prukop, Thomas, Nientiedt, Tobias, Albrecht, Philipp, Arlt, Friederike A, Stassart, Ruth M, Kassmann, Celia M, Methner, Axel, Nave, Klaus-Armin, Werner, Hauke B, Sereda, Michael W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554440/
https://www.ncbi.nlm.nih.gov/pubmed/26339673
http://dx.doi.org/10.1002/acn3.219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554440/
https://www.ncbi.nlm.nih.gov/pubmed/26339673
http://dx.doi.org/10.1002/acn3.219

Ejemplares similares