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F-box/LRR-repeat protein 7 is genetically associated with Alzheimer’s disease

OBJECTIVE: In the context of late-onset Alzheimer’s disease (LOAD) over 20 genes have been identified but, aside APOE, all show small effect sizes, leaving a large part of the genetic component unexplained. Admixed populations, such as Caribbean Hispanics, can provide a valuable contribution because...

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Detalles Bibliográficos
Autores principales: Tosto, Giuseppe, Fu, Hongjun, Vardarajan, Badri N, Lee, Joseph H, Cheng, Rong, Reyes-Dumeyer, Dolly, Lantigua, Rafael, Medrano, Martin, Jimenez-Velazquez, Ivonne Z, Elkind, Mitchell S V, Wright, Clinton B, Sacco, Ralph L, Pericak-Vance, Margaret, Farrer, Lindsay, Rogaeva, Ekaterina, St George-Hyslop, Peter, Reitz, Christiane, Mayeux, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554442/
https://www.ncbi.nlm.nih.gov/pubmed/26339675
http://dx.doi.org/10.1002/acn3.223