Cargando…

F-box/LRR-repeat protein 7 is genetically associated with Alzheimer’s disease

OBJECTIVE: In the context of late-onset Alzheimer’s disease (LOAD) over 20 genes have been identified but, aside APOE, all show small effect sizes, leaving a large part of the genetic component unexplained. Admixed populations, such as Caribbean Hispanics, can provide a valuable contribution because...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tosto, Giuseppe, Fu, Hongjun, Vardarajan, Badri N, Lee, Joseph H, Cheng, Rong, Reyes-Dumeyer, Dolly, Lantigua, Rafael, Medrano, Martin, Jimenez-Velazquez, Ivonne Z, Elkind, Mitchell S V, Wright, Clinton B, Sacco, Ralph L, Pericak-Vance, Margaret, Farrer, Lindsay, Rogaeva, Ekaterina, St George-Hyslop, Peter, Reitz, Christiane, Mayeux, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554442/ https://www.ncbi.nlm.nih.gov/pubmed/26339675 http://dx.doi.org/10.1002/acn3.223

Ejemplares similares

Rare coding mutations identified by sequencing of Alzheimer disease genome‐wide association studies loci
por: Vardarajan, Badri N., et al.
Publicado: (2015)

Rare Variants Imputation in Admixed Populations: Comparison Across Reference Panels and Bioinformatics Tools
por: Sariya, Sanjeev, et al.
Publicado: (2019)

Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease
por: Vardarajan, Badri N., et al.
Publicado: (2017)

Inbreeding among Caribbean Hispanics from the Dominican Republic and the Effects on the Risk of Alzheimer's Disease
por: Vardarajan, BN, et al.
Publicado: (2014)

Synonymous variants associated with Alzheimer disease in multiplex families
por: Tang, Min, et al.
Publicado: (2020)

Disease-related mutations among Caribbean Hispanics with familial dementia
por: Lee, Joseph H, et al.
Publicado: (2014)

Reliability and Validity of Self-Reported Vascular Risk Factors: Hypertension, Diabetes, and Heart Disease, in a Multi-Ethnic Community Based Study of Aging and Dementia
por: Lee, Annie J., et al.
Publicado: (2023)

Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)
por: Reitz, C, et al.
Publicado: (2013)

Progranulin mutations in clinical and neuropathological Alzheimer's disease
por: Vardarajan, Badri N., et al.
Publicado: (2022)

Lysophosphatidylcholines are associated with P-tau181 levels in early stages of Alzheimer’s Disease
por: Kalia, Vrinda, et al.
Publicado: (2023)

Admixture Mapping of Alzheimer’s disease in Caribbean Hispanics identifies a new locus on 22q13.1
por: Kizil, Caghan, et al.
Publicado: (2022)

Differences in plasma metabolites related to Alzheimer's disease, APOE ε4 status, and ethnicity
por: Vardarajan, Badri, et al.
Publicado: (2020)

Linkage analysis of multiplex Caribbean Hispanic families loaded for unexplained early-onset cases identifies novel Alzheimer's disease loci
por: Cheng, Rong, et al.
Publicado: (2018)

Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease
por: Vardarajan, Badri N., et al.
Publicado: (2018)

Risk of Alzheimer’s Disease is Associated with Longitudinal Changes in Plasma Biomarkers in the Multiethnic Washington Heights, Inwood Columbia Aging Project Cohort
por: Gu, Yian, et al.
Publicado: (2023)

Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease
por: Qiao, Min, et al.
Publicado: (2023)

The National Institute on Aging Late‐Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery
por: Reyes‐Dumeyer, Dolly, et al.
Publicado: (2022)

FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease
por: Lee, Annie J., et al.
Publicado: (2022)

Genetics and Genomics of Late-Onset Alzheimer's Disease and Its Endophenotypes
por: Reitz, Christiane, et al.
Publicado: (2011)

Genetic Variants in the Fat and Obesity Associated (FTO) Gene and Risk of Alzheimer's Disease
por: Reitz, Christiane, et al.
Publicado: (2012)

SORL1 mutations in early- and late-onset Alzheimer disease
por: Cuccaro, Michael L., et al.
Publicado: (2016)

Genomic variation in educational attainment modifies Alzheimer disease risk
por: Raghavan, Neha S., et al.
Publicado: (2019)

Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts
por: Vardarajan, Badri, et al.
Publicado: (2013)

Whole‐exome sequencing in 20,197 persons for rare variants in Alzheimer's disease
por: Raghavan, Neha S., et al.
Publicado: (2018)

Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease
por: Beecham, Gary W., et al.
Publicado: (2018)

Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly
por: Lee, Seonjoo, et al.
Publicado: (2018)

Evaluation of Plasma Biomarkers for A/T/N Classification of Alzheimer Disease Among Adults of Caribbean Hispanic Ethnicity
por: Honig, Lawrence S., et al.
Publicado: (2023)

Genome-wide Association Studies in Alzheimer’s Disease: A Review
por: Tosto, Giuseppe, et al.
Publicado: (2013)

Identification and characterization of the LRR repeats in plant LRR-RLKs
por: Chen, Tianshu
Publicado: (2021)

Correlation of plasma and neuroimaging biomarkers in Alzheimer's disease
por: Brickman, Adam M., et al.
Publicado: (2022)

Late-onset vs nonmendelian early-onset Alzheimer disease: A distinction without a difference?
por: Reitz, Christiane, et al.
Publicado: (2020)

A benchmark study on current GWAS models in admixed populations
por: Yang, Zikun, et al.
Publicado: (2023)

One for all and all for One: Improving replication of genetic studies through network diffusion
por: Lancour, Daniel, et al.
Publicado: (2018)

Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease
por: Lancour, Daniel, et al.
Publicado: (2020)

Effects of Vascular Risk Factors on the Association of Blood-Based Biomarkers with Alzheimer’s Disease
por: Hoost, SS, et al.
Publicado: (2023)

Early-Onset Alzheimer’s Disease: What Is Missing in Research?
por: Ayodele, Temitope, et al.
Publicado: (2021)

Plasma p‐tau181, p‐tau217, and other blood‐based Alzheimer's disease biomarkers in a multi‐ethnic, community study
por: Brickman, Adam M., et al.
Publicado: (2021)

Impact of Genetic Variation in SORCS1 on Memory Retention
por: Reitz, Christiane, et al.
Publicado: (2011)

Origin and Evolution of GALA-LRR, a New Member of the CC-LRR Subfamily: From Plants to Bacteria?
por: Kajava, Andrey V., et al.
Publicado: (2008)

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)–LRR oligomerization interface
por: Moghaddas, Fiona, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_r604di0aqgvo2ocv9uqls5co52