Comparative Analysis of Cesium Chloride- and Iodixanol-Based Purification of Recombinant Adeno-Associated Viral Vectors for Preclinical Applications

Cesium chloride (CsCl)- and iodixanol-based density gradients represent the core step in most protocols for serotype-independent adeno-associated virus (AAV) purification established to date. However, despite controversial reports about the purity and bioactivity of AAV vectors derived from each of...

Descripción completa

Detalles Bibliográficos
Autores principales: Strobel, Benjamin, Miller, Felix D., Rist, Wolfgang, Lamla, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554548/
https://www.ncbi.nlm.nih.gov/pubmed/26222983
http://dx.doi.org/10.1089/hgtb.2015.051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554548/
https://www.ncbi.nlm.nih.gov/pubmed/26222983
http://dx.doi.org/10.1089/hgtb.2015.051

Ejemplares similares