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Comparative Analysis of Cesium Chloride- and Iodixanol-Based Purification of Recombinant Adeno-Associated Viral Vectors for Preclinical Applications

Cesium chloride (CsCl)- and iodixanol-based density gradients represent the core step in most protocols for serotype-independent adeno-associated virus (AAV) purification established to date. However, despite controversial reports about the purity and bioactivity of AAV vectors derived from each of...

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Detalles Bibliográficos
Autores principales:	Strobel, Benjamin, Miller, Felix D., Rist, Wolfgang, Lamla, Thorsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554548/ https://www.ncbi.nlm.nih.gov/pubmed/26222983 http://dx.doi.org/10.1089/hgtb.2015.051

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