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Cytokines and growth factors cross-link heparan sulfate

The glycosaminoglycan heparan sulfate (HS), present at the surface of most cells and ubiquitous in extracellular matrix, binds many soluble extracellular signalling molecules such as chemokines and growth factors, and regulates their transport and effector functions. It is, however, unknown whether...

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Detalles Bibliográficos
Autores principales: Migliorini, Elisa, Thakar, Dhruv, Kühnle, Jens, Sadir, Rabia, Dyer, Douglas P., Li, Yong, Sun, Changye, Volkman, Brian F., Handel, Tracy M., Coche-Guerente, Liliane, Fernig, David G., Lortat-Jacob, Hugues, Richter, Ralf P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554917/
https://www.ncbi.nlm.nih.gov/pubmed/26269427
http://dx.doi.org/10.1098/rsob.150046