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Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors

Vertebrate NCoR-family co-repressors play central roles in the timing of embryo and stem cell differentiation by repressing the activity of a range of transcription factors. They interact with nuclear receptors using short linear motifs (SLiMs) termed co-repressor for nuclear receptor (CoRNR) boxes....

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Detalles Bibliográficos
Autores principales: Short, Stephen, Peterkin, Tessa, Guille, Matthew, Patient, Roger, Sharpe, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554918/
https://www.ncbi.nlm.nih.gov/pubmed/26289800
http://dx.doi.org/10.1098/rsob.150063