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Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts

Currently, human skin equivalents (HSEs) used for in vitro assays (e.g., for wound healing) make use of primary human skin cells. Limitations of primary keratinocytes and fibroblasts include availability of donor skin and donor variation. The use of physiologically relevant cell lines could solve th...

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Detalles Bibliográficos
Autores principales: Reijnders, Christianne M.A., van Lier, Amanda, Roffel, Sanne, Kramer, Duco, Scheper, Rik J., Gibbs, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554934/
https://www.ncbi.nlm.nih.gov/pubmed/26135533
http://dx.doi.org/10.1089/ten.tea.2015.0139