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Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts
Currently, human skin equivalents (HSEs) used for in vitro assays (e.g., for wound healing) make use of primary human skin cells. Limitations of primary keratinocytes and fibroblasts include availability of donor skin and donor variation. The use of physiologically relevant cell lines could solve th...
Autores principales: | Reijnders, Christianne M.A., van Lier, Amanda, Roffel, Sanne, Kramer, Duco, Scheper, Rik J., Gibbs, Susan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554934/ https://www.ncbi.nlm.nih.gov/pubmed/26135533 http://dx.doi.org/10.1089/ten.tea.2015.0139 |
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