2B4 Is Dispensable for T-Dependent B Cell Immune Responses, but Its Deficiency Leads to Enhanced T-Independent Responses Due to an Increase in Peritoneal Cavity B1b Cells

The signaling lymphocyte activation molecule (SLAM) family plays important roles in adaptive immune responses. Herein, we evaluated whether the SLAM family member 2B4 (CD244) plays a role in immune cell development, homeostasis and antibody responses. We found that the splenic cellularity in Cd244 (...

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Detalles Bibliográficos
Autores principales: Ray, Avijit, Yuan, Cheng-Yin, Miller, Nichole M., Mei, Hong, Dittel, Bonnie N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554987/
https://www.ncbi.nlm.nih.gov/pubmed/26323020
http://dx.doi.org/10.1371/journal.pone.0137314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554987/
https://www.ncbi.nlm.nih.gov/pubmed/26323020
http://dx.doi.org/10.1371/journal.pone.0137314

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