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2B4 Is Dispensable for T-Dependent B Cell Immune Responses, but Its Deficiency Leads to Enhanced T-Independent Responses Due to an Increase in Peritoneal Cavity B1b Cells
The signaling lymphocyte activation molecule (SLAM) family plays important roles in adaptive immune responses. Herein, we evaluated whether the SLAM family member 2B4 (CD244) plays a role in immune cell development, homeostasis and antibody responses. We found that the splenic cellularity in Cd244 (...
Autores principales: | Ray, Avijit, Yuan, Cheng-Yin, Miller, Nichole M., Mei, Hong, Dittel, Bonnie N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554987/ https://www.ncbi.nlm.nih.gov/pubmed/26323020 http://dx.doi.org/10.1371/journal.pone.0137314 |
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