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Identifying problematic drugs based on the characteristics of their targets

Identifying promising compounds during the early stages of drug development is a major challenge for both academia and the pharmaceutical industry. The difficulties are even more pronounced when we consider multi-target pharmacology, where the compounds often target more than one protein, or multipl...

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Detalles Bibliográficos
Autores principales: Lopes, Tiago J. S., Shoemaker, Jason E., Matsuoka, Yukiko, Kawaoka, Yoshihiro, Kitano, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555035/
https://www.ncbi.nlm.nih.gov/pubmed/26388775
http://dx.doi.org/10.3389/fphar.2015.00186