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Identifying problematic drugs based on the characteristics of their targets
Identifying promising compounds during the early stages of drug development is a major challenge for both academia and the pharmaceutical industry. The difficulties are even more pronounced when we consider multi-target pharmacology, where the compounds often target more than one protein, or multipl...
Autores principales: | Lopes, Tiago J. S., Shoemaker, Jason E., Matsuoka, Yukiko, Kawaoka, Yoshihiro, Kitano, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555035/ https://www.ncbi.nlm.nih.gov/pubmed/26388775 http://dx.doi.org/10.3389/fphar.2015.00186 |
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