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Structural analysis of Clostridium botulinum neurotoxin type D as a platform for the development of targeted secretion inhibitors
The botulinum neurotoxin type D is one of seven highly potent toxins produced by Clostridium botulinum which inhibit neurotransmission at cholinergic nerve terminals. A functional fragment derived from the toxin, LHn, consisting of the catalytic and translocation domains, has been heralded as a plat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555039/ https://www.ncbi.nlm.nih.gov/pubmed/26324071 http://dx.doi.org/10.1038/srep13397 |