Structural Modeling Insights into Human VKORC1 Phenotypes

Vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1) catalyses the reduction of vitamin K and its 2,3-epoxide essential to sustain γ-carboxylation of vitamin K-dependent proteins. Two different phenotypes are associated with mutations in human VKORC1. The majority of mutations cause resistance...

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Detalles Bibliográficos
Autores principales: Czogalla, Katrin J., Watzka, Matthias, Oldenburg, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555152/
https://www.ncbi.nlm.nih.gov/pubmed/26287237
http://dx.doi.org/10.3390/nu7085313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555152/
https://www.ncbi.nlm.nih.gov/pubmed/26287237
http://dx.doi.org/10.3390/nu7085313

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