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Structural Modeling Insights into Human VKORC1 Phenotypes

Vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1) catalyses the reduction of vitamin K and its 2,3-epoxide essential to sustain γ-carboxylation of vitamin K-dependent proteins. Two different phenotypes are associated with mutations in human VKORC1. The majority of mutations cause resistance...

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Detalles Bibliográficos
Autores principales:	Czogalla, Katrin J., Watzka, Matthias, Oldenburg, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555152/ https://www.ncbi.nlm.nih.gov/pubmed/26287237 http://dx.doi.org/10.3390/nu7085313

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