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Apple Polyphenols Decrease Atherosclerosis and Hepatic Steatosis in ApoE(−/−) Mice through the ROS/MAPK/NF-κB Pathway

In this study, we examined the effects of apple polyphenols (APs) on hyperlipidemia, atherosclerosis, hepatic steatosis and endothelial function and investigated the potential mechanisms. ApoE(−/−) mice were fed a western-type diet and orally treated with APs (100 mg/kg) or atorvastatin (10 mg/kg) f...

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Detalles Bibliográficos
Autores principales: Xu, Zhe-Rong, Li, Jin-You, Dong, Xin-Wei, Tan, Zhong-Ju, Wu, Wei-Zhen, Xie, Qiang-Min, Yang, Yun-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555163/
https://www.ncbi.nlm.nih.gov/pubmed/26305254
http://dx.doi.org/10.3390/nu7085324