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Silica bioreplication preserves three-dimensional spheroid structures of human pluripotent stem cells and HepG2 cells

Three-dimensional (3D) cell cultures produce more in vivo-like multicellular structures such as spheroids that cannot be obtained in two-dimensional (2D) cell cultures. Thus, they are increasingly employed as models for cancer and drug research, as well as tissue engineering. It has proven challengi...

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Detalles Bibliográficos
Autores principales: Lou, Yan-Ru, Kanninen, Liisa, Kaehr, Bryan, Townson, Jason L., Niklander, Johanna, Harjumäki, Riina, Jeffrey Brinker, C., Yliperttula, Marjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555166/
https://www.ncbi.nlm.nih.gov/pubmed/26323570
http://dx.doi.org/10.1038/srep13635