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One-Step Synthesis of Chiral Oxindole-type Analogues with Potent Anti-inflammatory and Analgesic Activities

Here we report a facile approach to synthesize highly optically active oxindole-type analogues with both high yield and enantioselectivity. This single-step synthesis strategy represents a substantial improvement upon existing methods that are often involved with multi-step routes and have suboptima...

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Detalles Bibliográficos
Autores principales: Sun, Yulong, Liu, Jia, Jiang, Xianxing, Sun, Tao, Liu, Luping, Zhang, Xiaoyuan, Ding, Shaoli, Li, Jingyi, Zhuang, Yan, Wang, Yiqing, Wang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555174/
https://www.ncbi.nlm.nih.gov/pubmed/26324065
http://dx.doi.org/10.1038/srep13699