Cargando…
One-Step Synthesis of Chiral Oxindole-type Analogues with Potent Anti-inflammatory and Analgesic Activities
Here we report a facile approach to synthesize highly optically active oxindole-type analogues with both high yield and enantioselectivity. This single-step synthesis strategy represents a substantial improvement upon existing methods that are often involved with multi-step routes and have suboptima...
Autores principales: | Sun, Yulong, Liu, Jia, Jiang, Xianxing, Sun, Tao, Liu, Luping, Zhang, Xiaoyuan, Ding, Shaoli, Li, Jingyi, Zhuang, Yan, Wang, Yiqing, Wang, Rui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555174/ https://www.ncbi.nlm.nih.gov/pubmed/26324065 http://dx.doi.org/10.1038/srep13699 |
Ejemplares similares
-
Anti-cancer small molecule JP-8g exhibits potent in vivo anti-inflammatory activity
por: Sun, Yulong, et al.
Publicado: (2014) -
Chiral ammonium betaine-catalyzed asymmetric Mannich-type reaction of oxindoles
por: Torii, Masahiro, et al.
Publicado: (2016) -
Adamantyl Analogues of Paracetamol as Potent Analgesic Drugs via Inhibition of TRPA1
por: Fresno, Nieves, et al.
Publicado: (2014) -
Asymmetric α-amination of 3-substituted oxindoles using chiral bifunctional phosphine catalysts
por: Jin, Qiao-Wen, et al.
Publicado: (2016) -
3-Arylidene-2-oxindoles as Potent NRH:Quinone Oxidoreductase 2 Inhibitors
por: Lozinskaya, Natalia A., et al.
Publicado: (2023)