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Targeted Modification of Gene Function Exploiting Homology-Directed Repair of TALEN-Mediated Double-Strand Breaks in Barley

Transcription activator-like effector nucleases open up new opportunities for targeted mutagenesis in eukaryotic genomes. Similar to zinc-finger nucleases, sequence-specific DNA-binding domains can be fused with effector domains like the nucleolytically active part of FokI to induce double-strand br...

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Detalles Bibliográficos
Autores principales: Budhagatapalli, Nagaveni, Rutten, Twan, Gurushidze, Maia, Kumlehn, Jochen, Hensel, Goetz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555222/
https://www.ncbi.nlm.nih.gov/pubmed/26153077
http://dx.doi.org/10.1534/g3.115.018762