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Structural implications of weak Ca(2+) block in Drosophila cyclic nucleotide–gated channels

Calcium permeability and the concomitant calcium block of monovalent ion current (“Ca(2+) block”) are properties of cyclic nucleotide–gated (CNG) channel fundamental to visual and olfactory signal transduction. Although most CNG channels bear a conserved glutamate residue crucial for Ca(2+) block, t...

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Detalles Bibliográficos
Autores principales: Lam, Yee Ling, Zeng, Weizhong, Derebe, Mehabaw Getahun, Jiang, Youxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555469/
https://www.ncbi.nlm.nih.gov/pubmed/26283200
http://dx.doi.org/10.1085/jgp.201511431