Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules

Cysteine-scanning mutagenesis combined with thiol reagent modification is a powerful method with which to define the pore-lining elements of channels and the changes in structure that accompany channel gating. Using the Xenopus laevis oocyte expression system and two-electrode voltage clamp, we perf...

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Detalles Bibliográficos
Autores principales: Tong, Xuhui, Lopez, William, Ramachandran, Jayalakshmi, Ayad, Wafaa A., Liu, Yu, Lopez-Rodriguez, Angelica, Harris, Andrew L., Contreras, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Methods and Approaches
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555470/
https://www.ncbi.nlm.nih.gov/pubmed/26324677
http://dx.doi.org/10.1085/jgp.201511375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555470/
https://www.ncbi.nlm.nih.gov/pubmed/26324677
http://dx.doi.org/10.1085/jgp.201511375

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