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Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules
Cysteine-scanning mutagenesis combined with thiol reagent modification is a powerful method with which to define the pore-lining elements of channels and the changes in structure that accompany channel gating. Using the Xenopus laevis oocyte expression system and two-electrode voltage clamp, we perf...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555470/ https://www.ncbi.nlm.nih.gov/pubmed/26324677 http://dx.doi.org/10.1085/jgp.201511375 |